The Significance of Neutrophil-Lymphocyte Ratio and Mean Corpuscular Volume in Diagnosis of Preeclampsia

Authors

  • Çağlar Yıldız Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Savaş Karakuş Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Özlem Bozoklu Akkar Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Tuğba Topbaş Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Meral Çetin Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Ali Yanık Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas
  • Ali Çetin Department of Obstetrics and Gynecology Cumhuriyet University School of Medicine, Sivas

DOI:

https://doi.org/10.21613/GORM.2016.84

Keywords:

Preeclampsia, Neutrophil to lymphocyte ratio, Mean corpuscular volume

Abstract

OBJECTIVE: The aim of this study is to evaluate the diagnostic values of neutrophil to lymphocyte ratio (NLR) and mean corpuscular volume (MCV) in patients with preeclampsia.
STUDY DESIGN: A retrospective analysis of patients with documented preeclampsia and uncomplicated pregnancy was carried out. Two hundred and twelve women with preeclampsia, and 58 healthy pregnant women as controls were included in the study. NLR and MCV values were calculated from complete blood count analysis.
RESULTS: White blood cell, NLR and MCV values were higher in the preeclamptic patients than those of the controls. The study groups had similar features with regard to the maternal age, gravidity, parity, and mode of delivery. Gestational age, newborn weight, and Apgar scores of the newborns were found lower in the preeclampsia group.
CONCLUSION: NLR may be helpful in the differential diagnosis of preeclampsia. Large-scale prospective studies with categorized study groups according to the severity of preeclampsia need to be performed to determine the optimal NLR values useful for the assessment of severity of preeclampsia.

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Published

2016-08-31

How to Cite

1.
Yıldız Çağlar, Karakuş S, Akkar Özlem B, Topbaş T, Çetin M, Yanık A, Çetin A. The Significance of Neutrophil-Lymphocyte Ratio and Mean Corpuscular Volume in Diagnosis of Preeclampsia. Gynecol Obstet Reprod Med [Internet]. 2016Aug.31 [cited 2022Jul.5];22(2):75-9. Available from: https://gorm.com.tr/index.php/GORM/article/view/84

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology