Indications for Human Albumin Infusion in a Neonatal Population: A Single Center Experience

Authors

  • Halil Degirmencioglu zekai tahir burak maternity teaching hospital
  • Birgul Say Derince Education and Research Hospital, ENT Clinic, 41100, Derince, Kocaeli, Turkey
  • Serife Suna Oguz

DOI:

https://doi.org/10.21613/GORM.2017.738

Keywords:

Newborn, Albumin, Outcome

Abstract

Objective: To evaluate the indications for human albumin infusion, the suitability of albumin infusion in neonatal intensive care units and neonatal outcomes after human albumin administration.

Study Design: Infants who had hypoalbuminemia (HAlb) (albumin level <20 g/L) and were given albumin infusion at any time during hospitalization between December 2012 and December 2013 were included in the study. Mortality (group 1 (alive), group 2 (died during hospitalization)) and morbidities were recorded. Demographic properties were assessed retrospectively.

Results: 38 neonates required HA transfusion therapy 61 times during the study, 89.5% were premature birth. 9 (23.7%) of 38 patients underwent major surgery. Group I =survived and are currently alive (n=22, 58%), Group II= died during hospitalization (n=16, 42%). In the groups, aspartate aminotransferase, creatinine and albumin levels were significantly different before and after infusion.

Conclusion: The value of HA in the clinical setting continues to be controversial and well-designed guidelines for its use in NICUs should be established for the neonatal period.

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Published

2018-04-30

How to Cite

1.
Degirmencioglu H, Say B, Oguz SS. Indications for Human Albumin Infusion in a Neonatal Population: A Single Center Experience. Gynecol Obstet Reprod Med [Internet]. 2018Apr.30 [cited 2022May26];24(1):47-51. Available from: https://gorm.com.tr/index.php/GORM/article/view/738

Issue

Section

Neonatology

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