The Diagnostic Accuracy of Endometrial Sampling in Endometrial Hyperplasia

Authors

  • Serdar Başaranoğlu Dr. Serdar BAŞARANOĞLU, MD Şemsipaşa Mahallesi 56. Sokak No: 2 Küçükköy –G.O.Paşa / ISTANBUL Phone: +90 212 444 95 75 Fax: +90 212 617 57 98 Mobile: +90 532 789 14 58 E-mail: [email protected]
  • Elif Ağaçayak Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır
  • Şafak Hatırnaz
  • Ayşegül Deregözü Bahçelievler State Hospital, Department of Obstetrics and Gynecology, Istanbul
  • Mustafa Acet Medipol University, Faculty of Medicine, Department of Obstetrics and Gynecology, Istanbul
  • Ebru Yüce Akropol Hospital, Department of Obstetrics and Gynecology, Ankara
  • Talip Karaçor Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır
  • Mehmet Sait İçen Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır
  • Mehmet Sıddık Evsen Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır
  • Talip Gül Dicle University, Faculty of Medicine, Department of Obstetrics and Gynecology, Diyarbakır

DOI:

https://doi.org/10.21613/GORM.2016.635

Keywords:

Endometrium, Hyperplasia, Curettage, Hysterectomy, Diagnostic disagreement

Abstract

Objective: Endometrial hyperplasia is a premalignant lesion characterized with hyperplastic changes in endometrial gland and stromal structures. Its incidence is not exactly known. This study evaluated the accuracy of endometrial sampling of the patients whose pathological results were endometrial hyperplasia and had undergone hysterectomy (paraffin sections).
Study Design: Patients that diagnosed with endometrial hyperplasia by endometrial biopsy and/or hysterectomy at Dicle University School of Medicine Department of Obstetrics and Gynecology between January 2006 and July 2014 were retrospectively evaluated. Sensitivity, specificity, and positive and negative predictive values of endometrial biopsy to predict postoperative hysterectomy result were calculated. Discrete results in endometrial sampling and hysterectomy were recorded separately. Statistical analyses were conducted with corresponding appropriate methods.
Results: Mean ages of pre and postmenopausal patients were 42.6±4.8 (28-50) and 57.7±7.7 (50-79) years, respectively. For the efficiency of endometrial sampling to predict definite pathologic diagnosis, sensitivity was 71.9%, specificity was 87.5%, positive predictive value was 79.3%, and negative predictive value was 82.3%. When the accuracy of endometrial sampling with the pathologic diagnosis was evaluated, 38 patients had accurate (47.5%), and 42 patients had discrete (52.5%) results.
Conclusion: The presence of atypia determines the treatment in patients with endometrial hyperplasia. Hysterectomy should not be the first option in endometrial hyperplasia patients without atypia, and medical treatment and curettage options should be considered. Experienced staff should perform and evaluate endometrial samplings. We consider that this will increase the success in diagnosis, and could change treatment options.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biography

Serdar Başaranoğlu, Dr. Serdar BAŞARANOĞLU, MD Şemsipaşa Mahallesi 56. Sokak No: 2 Küçükköy –G.O.Paşa / ISTANBUL Phone: +90 212 444 95 75 Fax: +90 212 617 57 98 Mobile: +90 532 789 14 58 E-mail: [email protected]

Bilge Hospital, Department of Obstetrics and Gynecology, 34240, Istanbul-Turkey

Downloads

Published

2017-04-28

How to Cite

1.
Başaranoğlu S, Ağaçayak E, Hatırnaz Şafak, Deregözü A, Acet M, Yüce E, Karaçor T, İçen MS, Evsen MS, Gül T. The Diagnostic Accuracy of Endometrial Sampling in Endometrial Hyperplasia. Gynecol Obstet Reprod Med [Internet]. 2017Apr.28 [cited 2022May26];23(1):37-40. Available from: https://gorm.com.tr/index.php/GORM/article/view/635

Issue

Section

Gynecology and Gynecological Oncology

Most read articles by the same author(s)

1 2 > >>