Chorionic Villus Sampling: Results of 135 High Risk Cases

Authors

  • İskender Başer Gülhane Military Medical Faculty, Department of Obstetrics and Gynecology, Etlik, Ankara
  • Sadettin Güngör Gülhane Military Medical Faculty, Department of Obstetrics and Gynecology, Etlik, Ankara
  • Ali Ergün Gülhane Military Medical Faculty, Department of Obstetrics and Gynecology, Etlik, Ankara

Keywords:

P renatal diagnosis, Chorionic villus sampling, Transabdominal, First-trimester, Outcome

Abstract

OBJECTIVE: To assess the data related to the first-trimester chorionic villus sampling performed in a single tertiary center.
STUDY DESIGN: Transabdominal CVS perf ormed on 135 pregnant women, aged 18 to 38 y ears, at 11 to 14 weeks’ gestation, who sought prenatal diagnosis for v arious reasons, during the years 2000-2004. Procedure related f etal loss rate, the indications, results of cytogenetic analy sis and the clinical outcomes of patients was obtained retrospectiv ely.
RESULTS: The indications f or prenatal diagnosis were enzymatic/DNA analysis f or single gene def ects (31.1%), adv anced positive screening test result (22.2%), advanced maternal age (17.8%), and maternal anxiety (11.9%). Kary oty ping was totally successful and chromosomal abnormality was detected in 3 women (2.2%). The procedure related f etal loss rate was 0.0%.
CONCLUSION: CVS perf ormed 11-14 weeks of gestation by experienced operators is a quick, reliable, and saf e diagnostic method for prenatal diagnosis and the ov erall incidence of antenatal and neonatal complications is no greater than that expected f or a general population.

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Published

2006-04-17

How to Cite

1.
Başer İskender, Güngör S, Ergün A. Chorionic Villus Sampling: Results of 135 High Risk Cases. Gynecol Obstet Reprod Med [Internet]. 2006Apr.17 [cited 2022Aug.10];12(1):12-5. Available from: https://gorm.com.tr/index.php/GORM/article/view/552

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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