A Comparison of Maternal and Fetal Outcomes of Pregnancies Complicated by Moderate to Severe Thrombocytopenia Caused by Gestational Thrombocytopenia Preeclampsia / HELLP Syndrome and Immune Thrombocytopenic Purpura

Authors

  • Suna Özdemir Department of Gynecology and Obstetric, Selçuk University Meram Medical Faculty, Konya
  • Hüseyin Görkemli Department of Gynecology and Obstetric, Selçuk University Meram Medical Faculty, Konya
  • Ali Acar Department of Gynecology and Obstetric, Selçuk University Meram Medical Faculty, Konya
  • Çetin Çelik Department of Gynecology and Obstetric, Selçuk University Meram Medical Faculty, Konya
  • Erkan Kayıkçıoğlu Department of Hematology, Selçuk University Meram Medical Faculty, Konya

Keywords:

Gestational thrombocytopenia, Preeclampsia/HELLP syndrome, Immune thrombocytopenic purpura, Fetal outcomes

Abstract

OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP).
STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course.
RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsia+HELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in
preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants.
CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.

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Published

2008-12-27

How to Cite

1.
Özdemir S, Görkemli H, Acar A, Çelik Çetin, Kayıkçıoğlu E. A Comparison of Maternal and Fetal Outcomes of Pregnancies Complicated by Moderate to Severe Thrombocytopenia Caused by Gestational Thrombocytopenia Preeclampsia / HELLP Syndrome and Immune Thrombocytopenic Purpura. Gynecol Obstet Reprod Med [Internet]. 2008Dec.27 [cited 2022Jan.18];14(3):154-8. Available from: https://gorm.com.tr/index.php/GORM/article/view/462

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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