Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report

Authors

  • Sibel Bektaş Department of Pathology Zonguldak Karaelmas University Faculty of Medicine, Zonguldak
  • Burak Bahadır Department of Pathology Zonguldak Karaelmas University Faculty of Medicine, Zonguldak
  • Figen Barut Department of Pathology Zonguldak Karaelmas University Faculty of Medicine, Zonguldak
  • Ülkü Bayar Department of Obstetric & Gynecology Zonguldak Karaelmas University Faculty of Medicine, Zonguldak
  • Şükrü Oğuz Özdamar Department of Pathology Zonguldak Karaelmas University Faculty of Medicine, Zonguldak

Keywords:

Serous carcinoma, Endometrial polyp, P53, C-erbB-2.

Abstract

Serous carcinoma is the prototype of type II endometrial carcinoma. A 71-year-old woman who had history of smoking, diabetes mellitus and hypertension admitted to the hospital with postmenopausal uterine bleeding. Curettage material was diagnosed as adenocarcinoma. Hysterectomy specimen revealed a uterine polypoid mass which afterwards was histopathologically proven to be a serous carcinoma arising from an endometrial polyp. Immunohistochemically, tumor cells showed diffuse reaction for p53 and c-erbB-2, and focal reaction for estrogen and progesterone receptors. In addition to history of diabetes mellitus and hypertension, our case shared some clinical and immunohistochemical characteristics of type I endometrial carcinoma, such as focal expression of estrogen and progesterone receptors. Overexpressions of p53 and c-erbB-2 in this tumor type should be considered.

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Published

2009-04-11

How to Cite

1.
Bektaş S, Bahadır B, Barut F, Bayar Ülkü, Özdamar Şükrü O. Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report. Gynecol Obstet Reprod Med [Internet]. 2009Apr.11 [cited 2022Jul.7];15(1):57-60. Available from: https://gorm.com.tr/index.php/GORM/article/view/386

Issue

Section

Case Reports

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