Amniotic Fluid β2- Microglobulin Measurements

Authors

  • Emine Aydın Hacettepe University Medical Faculty, Division of Perinatal Medicine, Ankara
  • Alp Tuna Beksaç Hacettepe University Medical Faculty, Department of Urology, Ankara
  • Ergün Karaağaoğlu Hacettepe University Medical Faculty, Department of Bioistatistics, Ankara
  • M. Sinan Beksaç Hacettepe University Medical Faculty, Division of Perinatal Medicine, Ankara

Keywords:

Amniotic fluid, β2-microglobulin, Second trimester

Abstract

OBJECTIVE: To determine β2-microglobulin levels in amniotic fluid during the course of second trimester.

STUDY DESIGN: One hundred patient’s amniotic fluid β2-microglobulin levels had been evaluated retrospectively (March-October 2009). The most common amniocentesis indication was advanced maternal age (33.3%). Others were; high risk result for triple test (18.5%), high risk result for double test (6.48%), ventriculomegaly (5.55%), obstetric history for fetus with down syndrome (4.62%), the presence of soft markers on ultrasound (13.8%), others (17.8%). Patients average gravida was 2.66 (range: 1-6), parity was 0.75 (range: 0-3), abortion was 0.65 (range: 0-3).

RESULTS: All patients were at second trimester and the average gestational week was 17.7 (range 15- 22). Patients were divided into four groups (15th, 16th, 17-18th and 19-20th gestational weeks). We have demonstrated that amniotic fluid β2-microglobulin levels are increased progressively throughout the second trimester. We have specified normal β2-microglobulin values of each gestational week/period in order to be used in clinical practice.

CONCLUSION: We have demonstrated that amnionic fluid β2-microglobulin levels are increased progressively throughout the second trimester.

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Published

2015-04-30

How to Cite

1.
Aydın E, Beksaç AT, Karaağaoğlu E, Beksaç MS. Amniotic Fluid β2- Microglobulin Measurements. Gynecol Obstet Reprod Med [Internet]. 2015Apr.30 [cited 2022May26];21(1):1-3. Available from: https://gorm.com.tr/index.php/GORM/article/view/35

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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