Gastrointestinal Stromal Tumor Mimicking Ovarian Tumor

Authors

  • Özlem Seçilmiş Kerimoğlu Selçuk Univercity Selçuklu Medicine Faculty, Obstetrics and Gynecology, Konya
  • Füsun Baba Selçuk Univercity Selçuklu Medicine Faculty, Pathology, Konya
  • Aybike Tazegül Selçuk Univercity Selçuklu Medicine Faculty, Obstetrics and Gynecology, Konya
  • Hüsnü Alptekin Selçuk Univercity Selçuklu Medicine Faculty, Obstetrics and Gynecology, Konya
  • Hasan Acar Selçuk Univercity Selçuklu Medicine Faculty, Obstetrics and Gynecology, Konya
  • Çetin Çelik Selçuk Univercity Selçuklu Medicine Faculty, Obstetrics and Gynecology, Konya

Keywords:

Gastrointestinal stromal tumor, Ovary

Abstract

Malignant gastrointestinal stromal tumors are rare mesenchymal tumors originating from the gastrointestinal tract. Making a differential diagnosis with gynecologic masses may be difficult in the preoperative period. The patient was a 45- year-old woman who presented to our clinic with a palpable mass filling the pelvis. The CA 125 value was 42.7 U/ml. She underwent right hemicolectomy, total omentectomy,
total abdominal hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic and para-aortic lymph node dissection since the frozen section assessment of the biopsy from the right colon was reported as a tumoral mass probably originating from the ovary. Tumoral tissue showed diffuse cytoplasmic membraneous staining immunohistochemically with CD117, showed strong focal strong cytoplasmic
staining with SMA. It was stained negative with desmin, S-100 and CD34. Molecular analysis of KIT gene was performed, we didn't detect mutations of exon 9 or 11. Surgical exploration of pelvic masses with undetermined origins should be performed in multidiciplinary hospitals including gynecological oncology and surgical oncology teams. Histopathological examinations should be performed by experienced pathologists.

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Published

2012-12-06

How to Cite

1.
Seçilmiş Kerimoğlu Özlem, Baba F, Tazegül A, Alptekin H, Acar H, Çelik Çetin. Gastrointestinal Stromal Tumor Mimicking Ovarian Tumor. Gynecol Obstet Reprod Med [Internet]. 2012Dec.6 [cited 2022May27];18(3):170-2. Available from: https://gorm.com.tr/index.php/GORM/article/view/274

Issue

Section

Case Reports

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