Pelvic Ectopic Adrenal Tissue Leading to Benign Gynecological Pathologies in a Mosaic Turner’s Syndrome Patient: A Case Report

Authors

  • Aslıhan Yazıcıoğlu Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine, Ankara
  • Özge Senem Yücel Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine, Ankara
  • Mert Turğal Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine, Ankara
  • Ferdi Vaizoğlu Department of Obstetrics and Gynecology Karayazı State Hospital, Erzurum
  • Özlem Tanas Department of Pathology Hacettepe University Faculty of Medicine, Ankara
  • Kemal Beksaç Department of General Surgery Hacettepe University Faculty of Medicine, Ankara
  • Bülent Tırnaksız Department of General Surgery Hacettepe University Faculty of Medicine, Ankara
  • Alp Usubütün Department of Pathology Hacettepe University Faculty of Medicine, Ankara
  • Sinan Beksaç Department of Obstetrics and Gynecology Hacettepe University Faculty of Medicine, Ankara

Keywords:

Mosaic turner’s syndrome, Myoma, Secretory endometrium, Ectopic adrenal tissue

Abstract

Benign gynecological pathologies in patients with Turner’s syndrome were described in the medical literature. Herein, we present a 39-year-old woman with mosaic Turner’s syndrome (45,0X/46,X,i(X)q10) complaining about bleeding and persistent pelvic pain. In physical examination, she presented normal secondary sex development, normal breast, normal pubic and axillary hair. The external genitalia were also normal. Her laboratory examination showed elevated gonadotropin levels, decreased 17betaestradiol levels and normal plasma androgens and cortisol levels. At transabdominal ultrasonography multiple myoma and irregular thickening of the endometrium were suspected. At laparotomy, total abdominal hysterectomy and bilateral salpingectomy were performed. Histopathological examination revealed multiple leiomyoma, secretory endometrium and ectopically localized adrenal tissue. Since its known that both myoma uteri and secretory changes in endometrium develop primarily in woman of reproductive age and their growth is estrogen dependent, the source of estrogen in the present case was thought to
be the ectopic adrenal tissue located just beneath the left salpinx. This seems to be the first report of the occurence of benign gynecological pathologies due to the ectopic adrenal tissue in a mosaic Turner’s syndrome patient without hormone replacement therapy.

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Published

2012-12-06

How to Cite

1.
Yazıcıoğlu A, Yücel Özge S, Turğal M, Vaizoğlu F, Tanas Özlem, Beksaç K, Tırnaksız B, Usubütün A, Beksaç S. Pelvic Ectopic Adrenal Tissue Leading to Benign Gynecological Pathologies in a Mosaic Turner’s Syndrome Patient: A Case Report. Gynecol Obstet Reprod Med [Internet]. 2012Dec.6 [cited 2022May20];18(3):163-5. Available from: https://gorm.com.tr/index.php/GORM/article/view/271

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Section

Case Reports

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