Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus?

Authors

  • Mehmet Metin Altay Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Serdinç Özdoğan Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Aytaç Tohma Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Sertaç Esin Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Okyar Erol Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Orhan Gelişen Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Melih Akkuş Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara
  • Sinan Karadeniz Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, Ankara

Keywords:

Gestational diabetes mellitus, Screening, Diagnosis, 100 g oral glucose tolerance test

Abstract

OBJECTIVE: To investigate whether the 3rd hour value of 100 g oral glucose tolerance test (OGTT) can be ignored when diagnosing gestational diabetes.
STUDY DESIGN: During the first 8 months of 2010, 6909 patients between 24 and 28 weeks’ of gestation were screened with 50 g glucose challenge test and 140 mg/dl or higher plasma glucose levels were further evaluated with 100 g OGTT to diagnose gestational diabetes mellitus (GDM). 1195 patients’ test results were acquired for this retrospective study. For the 100 g OGTT fasting plasma glucose cut-off value was 105 mg/dl, 1 hour cut-off value was 190 mg/dl, 2 hour cut-off value was 165 mg/dl and 3 hour cut-off value was 145 mg/dl. Patients with 2 or more values above the cut-off level were diagnosed as GDM.
RESULTS: Out of 1195, 124 patients (10.4%) were diagnosed as having GDM. 65 patients (52.4%) had high values of first and second hours; 33 patients (26.6%) had high values of first, second and third hours; 19 patients (15.4%) had second and third hours high values; 7 patients (5.6%) had first and third hours high values of 100 gr OGTT out of those 124 patients.
CONCLUSION: 79% of the patients were diagnosed with first and second hour test results but 21% of the patients were diagnosed with blood glucose levels above the third hour cut-off level. Thus, considering the difficulties of 100 gr. OGTT, third hour values is of diagnostic value and cannot be ignored.

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Published

2013-12-30

How to Cite

1.
Altay MM, Özdoğan S, Tohma A, Esin S, Erol O, Gelişen O, Akkuş M, Karadeniz S. Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus?. Gynecol Obstet Reprod Med [Internet]. 2013Dec.30 [cited 2021Sep.26];19(3):157-61. Available from: https://gorm.com.tr/index.php/GORM/article/view/209

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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