Low - dose Computed Tomography Perfusion study to Differentiate Between Benign and Malignant Ovarian Tumors

Arpit Garg; Ritu Misra; Neha Bagri; Saritha  Shamsunder

doi:10.21613/GORM.2025.1555

Low - dose Computed Tomography Perfusion study to Differentiate Between Benign and Malignant Ovarian Tumors

Authors

Arpit Garg Department of Radiodiagnosis, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi -110029, India. https://orcid.org/0009-0008-9012-6008
Ritu Misra Department of Radiodiagnosis, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi -110029, India. https://orcid.org/0000-0001-9322-8685
Neha Bagri VMMC & Safdarjung Hospital, New Delhi 110029 https://orcid.org/0000-0002-4883-1300
Saritha Shamsunder Department of Radiodiagnosis, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi -110029, India. https://orcid.org/0000-0002-6539-5598

DOI:

https://doi.org/10.21613/GORM.2025.1555

Keywords:

Abdomen, Benign ovarian tumors, Blood, CT scanner , Malignant ovarian tumors , Perfusion computed tomography , Volume

Abstract

OBJECTIVE: To assess the role of Low-dose perfusion computed tomography (PCT) in differentiating benign and malignant ovarian tumors.

STUDY DESIGN: Low-dose PCT (80 kVp and 120 mAs on a 256-slice CT scanner) was performed on fifty-one pathologically proven benign and malignant ovarian tumors. The PCT parameters calculated were blood flow (BF), blood volume (BV), time to maximum (T max), mean transit time (MTT), and flow extraction product (FED). Statistical analysis was performed to evaluate the association between these PCT parameters and histopathological diagnosis.

RESULTS: The study comprised 31 pathologically confirmed malignant and 20 benign ovarian tumors. The mean BF, BV, and FED values were elevated in malignant tumors and showed statistically significant association (p<0.001). However, MTT and T max were not statistically significant. The average radiation dose for the entire study was 13.5 mSv, slightly lower than that of standard NCCT and CECT abdomen scans performed for staging purposes.

CONCLUSION: Low-dose PCT parameters (BF, BV, and FED) can play a significant role in differentiating benign from malignant ovarian tumors.

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Published

2025-04-28

How to Cite

Garg A, Misra R, Bagri N, Shamsunder S. Low - dose Computed Tomography Perfusion study to Differentiate Between Benign and Malignant Ovarian Tumors. Gynecol Obstet Reprod Med [Internet]. 2025Apr.28 [cited 2026May16];31(1):71-7. Available from: https://gorm.com.tr/index.php/GORM/article/view/1555

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Issue

Vol. 31 No. 1 (2025):

Section

Gynecology and Gynecological Oncology

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