Pregnancy Outcomes of Infertile Patients Presenting to Our Assisted Reproductive Technology Center

Abstract

OBJECTIVE: In this study, we aimed to evaluate whether the demographic and stimulation characteristics, treatment results, and pregnancy outcomes of infertile couples who applied to our assisted reproductive technology center vary according to the calendar year.

STUDY DESIGN: The original files of 949 patients who underwent assisted reproductive technology treatment were analyzed between January 2012 and December 2017. Assisted reproductive technology cycles were classified according to year and also basal parameters and assisted reproductive technology outcomes were compared by year.

RESULTS: Female age, infertility period, baseline follicle-stimulating hormone, luteinizing hormone, estradiol levels, duration of stimulation, total gonadotropin dose required, peak E2 level, and endometrial thickness on human chorionic gonadotropin administration day were statistically significant between the groups (p<0.05). While a statistically significant difference was observed in fertilization rate (p<0.05), the following were comparable between the groups (p>0.05): number of retrieved and MII oocytes, two pronuclei, day of transfer, embryo transfer technique, single vs. multiple embryo transfer, rates of the Grade-I embryo, biochemical and clinical pregnancy, live birth, ectopic pregnancy, and miscarriage.

CONCLUSION: Infertile women of reproductive age benefit from assisted reproductive technology when trying to become pregnant. Factors that could adversely affect assisted reproductive technology, such as advanced age, have a negative impact on the treatment’s success. These repercussions should be taken into account by infertile couples who consider delaying pregnancy.