Biochemical Markers As Predictor Of Preterm Labor- Their Clinical Relevance And The Current Status

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DOI:

https://doi.org/10.21613/GORM.2020.1108

Keywords:

preterm birth (PTB), preterm delivery (PTD), phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1), placental alpha macroglobulin-1 (PAMG-1)

Abstract

Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm birth accounts for upto 75% of all preterm births. A number of maternal and fetal characteristics have been associated with preterm birth. With better understanding of the pathophysiology of preterm birth, various biochemical markers have been studied extensively to predict the preterm birth efficiently so as to intervene appropriately and timely in the cases that would benefit from treatment. This paper provides a summary of the current literature on the use of biochemical markers in predicting spontaneous preterm birth in symptomatic and high risk-asymptomatic women. Evidence from the literature suggests cervico vaginal fetal fibronectin,interleukin-6, phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1), placental alpha macroglobulin-1 (PAMG-1) and serum

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Author Biographies

Suneeta Singh, Lt Col Suneeta Singh Asst Professor, Department of Obstetrics and Gynaecology Base Hospital, Delhi Cantt New Delhi India

Lt Col Suneeta Singh

Asst Professor,
Department of Obstetrics and Gynaecology
Base Hospital, Delhi Cantt
New Delhi
India

Madhusudhan Dey, Colonel Madhusudan Dey Associate Professor Department of Obstetrics and Gynaecology Base Hospital Delhi Cantt New Delhi

Colonel Madhusudan Dey
Associate Professor and Senior Advisor
Department of Obstetrics and Gynaecology
Base Hospital Delhi Cantt
New Delhi

Sanjay Singh, Colonel Sanjay Singh Professor Department of Obstetrics and Gynaecology Base Hospital Delhi Cantt New Delhi

Colonel Sanjay Singh
Professor and Senior Advisor
Department of Obstetrics and Gynaecology
Base Hospital Delhi Cantt
New Delhi

Shibu Sasidharan, Lt Col Shibu Sasidharan Associate Professor Department of Anaesthesia and Critical Care Level III UN hospital

Lt Col Shibu Sasidharan
Team Leader
Department of Anaesthesia and Critical Care
Level III UN hospital

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Published

2020-12-27

How to Cite

1.
Singh S, Dey M, Singh S, Sasidharan S. Biochemical Markers As Predictor Of Preterm Labor- Their Clinical Relevance And The Current Status. Gynecol Obstet Reprod Med [Internet]. 2020Dec.27 [cited 2022Jul.7];:1-8. Available from: https://gorm.com.tr/index.php/GORM/article/view/1108

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Section

Review

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