The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness

Authors

  • Kerem Doğa Seçkin Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul
  • Mehmet Fatih Karslı Department of Obstetrics and Gynaecology, Sami Ulus Women and Children Health Training and Research Hospital, Ankara
  • Burak Yücel Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul
  • Elif Akkaş Yılmaz Department of Obstetrics and Gynaecology, Sami Ulus Women and Children Health Training and Research Hospital, Ankara
  • Murat Öz Department of Obstetrics and Gynaecology, Zekai Tahir Burak Womens’ Health and Research Hospital, Ankara
  • Deniz Balsak Department of Obstetrics and Gynaecology, Halic University, Istanbul
  • Hüseyin Kıyak Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul
  • Gökhan Yıldırım Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul

DOI:

https://doi.org/10.21613/GORM.2016.108

Keywords:

Mean platelet volume, Endometrial thickness, Submucosal myoma

Abstract

OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding.
STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups.
RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p>0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p<0,05).
CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure.

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Published

2016-04-29

How to Cite

1.
Seçkin KD, Karslı MF, Yücel B, Yılmaz EA, Öz M, Balsak D, Kıyak H, Yıldırım G. The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness. Gynecol Obstet Reprod Med [Internet]. 2016Apr.29 [cited 2024Mar.29];22(1):32-5. Available from: https://gorm.com.tr/index.php/GORM/article/view/108

Issue

Section

Gynecology and Gynecological Oncology