TY - JOUR AU - Budak, Mehmet Şükrü AU - Akgöl, Sedat AU - Önen, Şahin AU - Erdem, Selami AU - Kahyaoğlu, Serkan AU - Kanat Pektaş, Mine PY - 2012/08/06 Y2 - 2024/03/29 TI - Is Weekly Supplementation of Vitamin D Favorable for Treatment of Osteoporosis in Postmenopausal Women? JF - Gynecology Obstetrics & Reproductive Medicine JA - Gynecol Obstet Reprod Med VL - 18 IS - 2 SE - Gynecology and Gynecological Oncology DO - UR - https://gorm.com.tr/index.php/GORM/article/view/245 SP - 78-82 AB - <p>OBJECTIVE: The present study aims to determine whether once weekly supplementation of vitamin D and alendronate is efficient and safe for treatment of postmenopausal osteoporosis.<br />STUDY DESIGN: Group I (42 women with postmenopausal osteoporosis) received daily supplementation of calcium (1000 mg) and vitamin D (880 IU) while group II (42 women with postmenopausal osteoporosis) had weekly supplementation of vitamin D (2800 IU) along with weekly treatment of alendronate (70 mg).<br />RESULTS: Group I had significantly lower lumbar spine T-scores before and after treatment. Post-treatment lumbar spine T-scores and femur neck T-scores were significantly higher with respect to pre-treatment scores in both study groups. The alterations in lumbar spine and femur neck T-scores were statistically similar in both group I and group II.<br />CONCLUSION: Once weekly administration of vitamin D and alendronate is an effective and safe option of treatment for women who cannot take calcium supplements for postmenopausal osteoporosis.</p> ER -