TY - JOUR AU - Bayoğlu Tekin, Yeşim AU - Güvendağ Güven, Emine Seda AU - Yazıcı, Zihni Açar AU - Kırbaş, Aynur AU - Kır Şahin, Figen PY - 2014/12/30 Y2 - 2024/03/29 TI - Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus JF - Gynecology Obstetrics & Reproductive Medicine JA - Gynecol Obstet Reprod Med VL - 20 IS - 3 SE - Reproductive Medicine: Endocrinology and Infertility DO - UR - https://gorm.com.tr/index.php/GORM/article/view/164 SP - 159-162 AB - <p>OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus.<br />STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month period. The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 days after the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-glycosaminoglycans (s-GAG) were evaluated.<br />RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher than those of the controls. However, the difference was statistically significant only for s-GAG (p&lt;0.001).<br />CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.</p> ER -