Neuroendocrıne Small Cell Carcinoma of the Endometrium: A Case Presentation

Authors

  • Hüseyin Görkemli Department Of Obstetrics and Gynecology, Selcuk University Meram Medical School, Konya
  • Kazım Gezginç Department Of Obstetrics and Gynecology, Selcuk University Meram Medical School, Konya
  • Fatma Yazıcı Department Of Pathology Selcuk University Meram Medical School, Konya
  • Utku Dalkılıç Department Of Pathology Selcuk University Meram Medical School, Konya
  • Salim Güngör Department Of Pathology Selcuk University Meram Medical School, Konya

Keywords:

Endometrium, Small cell carcinoma, Neuroendocrine differentiation.

Abstract

To present a case of neuroendocrine differentiated small cell carcinoma of the endometrium with postmenopausal bleeding and its clinical, histological and immunohistochemical features are discussed. A 54-year-old woman (gravida 4, para 1), admitted to our clinic with a chief complaint of postmenopausal bleeding for 1 months. She has been in menopause for 10 years. On pelvic examination, she had 3 months-sized, firm, large, hard, and anteverted uterus. Cervicovaginal smear was normal. A subsequent endometrial curettage was suspicious for carcinoma. The patient underwent total abdominal hysterectomy with bilateral salpingooophorectomy and pelvic lymphadenectomy. Malignancy was confirmed from frozen section. The final pathology report confirmed neuroendocrine differentiated small cell carcinoma of the endometrium. The postoperative course was uneventful and the patient received chemotherapy including cisplatin and etoposide. These tumors have a propensity for systemic spread and poor prognosis; therefore, the stage of the tumor is an important prognostic factor. Early detection provides the only opportunity for long-term survival in patients with small cell carcinoma of endometrium.

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Published

2011-12-10

How to Cite

1.
Görkemli H, Gezginç K, Yazıcı F, Dalkılıç U, Güngör S. Neuroendocrıne Small Cell Carcinoma of the Endometrium: A Case Presentation. Gynecol Obstet Reprod Med [Internet]. 2011Dec.10 [cited 2022Aug.8];17(3):188-90. Available from: https://gorm.com.tr/index.php/GORM/article/view/324

Issue

Section

Case Reports

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