Iodine Levels in Pregnant Women with Hyperemesis Gravidarum

Seyma Banu Arslanca
Vakkas korkmaz
Tufan Arslanca
Figen Besyaprak
Adil Barut
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Objective: Iodine deficiency is a commonly seen problem and associated with pregnancy complications. In this study, we aimed to evaluate urinary iodine status in pregnant women with hyperemesis gravidarum

Study Design: A total of 121 women experiencing singleton pregnancies between 6 and 18 weeks of gestation were included in the study. The participants were divided into two groups; group 1 comprised 81 healthy pregnant women, and group 2 comprised 40 pregnant women with Hyperemesis Gravidarum.

Results: Urinary iodine levels were found to be significantly higher in healthy pregnant women than women with Hyperemesis Gravidarum (p=0.008). Urinary iodine was significantly correlated with the urinary ketone (r= -0.252, p=0.005) and FT3 (r= -0.190, p=0.037).

Conclusion: In pregnant women with hyperemesis gravidarum, oxidative stress was increased, urinary iodine levels were significantly low and negatively correlated with disease severity. Thus, ıodine replacement might be essential to prevent pregnancy complications.


Hyperemesis gravidarum, Oxidative stress, Urinary iodine


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