A Rare Gestational Trophoblastic Disease: Placental Site Trophoblastic Tumor

Senem Yaman Tunç
Elif Ağaçayak
Mehmet Sait İçen
Serdar Başaranoğlu
Mehmet Sıddık Evsen
Yahya Avcı
Zuhat Urakcı
Talip Gül
Full Text: PDF


Placental site trophoblastic tumor (PSTT) is a highly rare form of gestational trophoblastic diseases that arise from intermediate trophoblastic cells. By presenting this case, we aimed to review the treatment and diagnosis, approach to PSTT.
A 31-year-old (G2P1A1L1) patient had abnormal vaginal bleeding. Serum ß-HCG was 5.82 mIU/ml and the transvaginal USG detected a polypoid mass in uterine cavity. Probe curettage was performed. Histopathologic specimens were confirmed as PSTT. No metastasis was detected. A total abdominal hysterectomy was performed.
PSTT is a rare tumor. In contrast to other trophoblastic tumors, PSTT produces a small amount of ß-HCG and it is relatively insensitive to chemotherapy. Adjuvant chemotherapy is suggested to follow surgical treatment in the cases with metastasis.


Placental site trophoblastic tumor, Low ß-HCG, Hysterectomy, Chemotherapy.

DOI: http://dx.doi.org/10.21613/GORM.2016.485

Copyright (c) 2016 Gynecology Obstetrics & Reproductive Medicine

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.