Prenatal Invasive Testing: A 4-Years Single Institution Experience in Turkey

Emre Ekmekçi
Kutlu Kurt
Servet Gençdal
Emine Demirel
Sefa Kelekçi
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OBJECTIVE: Evaluation of indications, methods and results of prenatal diagnostic invasive procedures performed in our clinic in a four-year process and interpretation of relations between them.

STUDY DESIGN: In this study 553 patients were examined retrospectively, who were undergone prenatal invasive procedures in our clinic for determination of fetal karyotype. Demographic distribution of the patients, indications for tests and results were examined, complications were evaluated depending on the procedure.

RESULTS: A total of 41 abnormal karyotype pregnancies detected, the most common abnormal karyotype was trisomy 21 and most of abnormal karyotypes were detected in patients who undergone invasive diagnostic tests due to abnormal ultrasound findings. Abortion is resulted at two patients.

CONCLUSION: Although non-invasive prenatal diagnosis is more accessible today and has become more preferable, prenatal invasive diagnosing still remains its importance in prenatal diagnosis. Especially in the cases with presence of abnormal ultrasound findings, invasive prenatal diagnosis should be the primary diagnostic method.


Prenatal invasive test, Fetal karyotype, Trisomy 21

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